# Down with Disease guitar solo

> Trey Anastasio's guitar solo on Down with Disease by Phish (1994) starts at about 2:08. From the album Hoist. Played on a Languedoc.

Canonical URL: <https://greatestsolos.com/song/phish-down-with-disease/>

Phish, 1994, from *Hoist*. Solo by *Trey Anastasio*.

The studio solo is a tight, ripping burst, and the song became one of Phish's great open-ended live jam vehicles.

Down with Disease by Phish is #16 in our ranking of the best Phish guitar solos. The solo is played by Trey Anastasio and the song was released in 1994.

## In our lists

- [The Best Phish Guitar Solos](https://greatestsolos.com/list/phish-guitar-solos/) — #16

## Sources

### Who played the guitar solo on Down with Disease?

Trey Anastasio played the solo on Phish's Down with Disease (1994).

### What guitar was used on the Down with Disease solo?

A languedoc, according to widely reported accounts.

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