# Handshake Drugs guitar solo

> Nels Cline's guitar solo on Handshake Drugs by Wilco (2005) starts at about 4:00. From the album Kicking Television: Live in Chicago.

Canonical URL: <https://greatestsolos.com/song/wilco-handshake-drugs/>

Wilco, 2005, from *Kicking Television: Live in Chicago*. Solo by *Nels Cline*.

Live, the song swells into a noisy guitar climax that immediately announced Cline's arrival in the band.

Handshake Drugs by Wilco is #5 in our ranking of the best Nels Cline guitar solos. The solo is played by Nels Cline and the song was released in 2005.

## In our lists

- [The Best Nels Cline Guitar Solos](https://greatestsolos.com/list/nels-cline-guitar-solos/) — #5
- [The Best Wilco Guitar Solos](https://greatestsolos.com/list/wilco-guitar-solos/) — #5

## Sources

### Who played the guitar solo on Handshake Drugs?

Nels Cline played the solo on Wilco's Handshake Drugs (2005).

### What guitar was used on the Handshake Drugs solo?

A fender jazzmaster, according to widely reported accounts.

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