You and I
Lady Gaga, 2011. Solo by Brian May.
May's layered, instantly recognisable tone turns Gaga's piano rocker into an affectionate nod to Queen.
You and I is a piano-driven rocker, and Brian May's guitar solo turns it into an affectionate nod to Queen. His tone is instantly recognisable: smooth, singing and layered, with harmonised lines stacked into a rich, orchestral sound. He plays with melody first, crafting phrases that feel composed rather than improvised, much like his classic 1970s work. Hearing May on a 2011 pop hit shows how much his approach has shaped modern rock guitar. Listen for the harmony parts that blend into a single, choir-like voice, and for how the solo builds naturally from the song's chords, adding drama and warmth without overwhelming Gaga's vocal or the song's heartfelt, retro feel.
You and I by Lady Gaga is featured in our Pop (#17) list. The solo is played by Brian May and the song was released in 2011.
In our lists
Sources
Who played the guitar solo on You and I?
Brian May played the solo on Lady Gaga's You and I (2011).